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Arthrosamid Injection

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What is Arthrosamid®

Arthrosamid® is a ground-breaking injectable hydrogel designed to relieve pain and stiffness caused by knee osteoarthritis. It is a proven, non-operative treatment that helps reduce discomfort and improve mobility in a carefully selected group of patients who are not ready—or may wish to delay—knee replacement surgery.

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This innovative treatment works by cushioning and lubricating the knee joint from within, reducing inflammation and improving movement. Unlike other injections such as corticosteroids or hyaluronic acid, Arthrosamid® stays in the joint long-term, providing ongoing relief that can last for several years

How does Arthrosamid® work?

Arthrosamid® is an advanced, minimally invasive treatment for knee osteoarthritis. It is a single-dose injectable hydrogel implant, composed of 2.5% cross-linked polyacrylamide and 97.5% water, designed to integrate with the synovial tissue of the knee joint

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When Arthrosamid® is injected into the joint space, it distributes within the synovial fluid and adheres into the synovial lining, forming a soft but stable visco-elastic layer.


This hydrogel integration helps to:

  • Cushion the joint and improve glide between surfaces

  • Provide sustained mechanical support to reduce pain and stiffness

  • Improve joint function and mobility in daily activities

  • Offer a long-lasting non-surgical alternative for patients with knee arthritis

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Who Might Benefit from Arthrosamid®?

Arthrosamid® is suitable for patients with mild to moderate knee osteoarthritis who:

  • Have persistent pain and stiffness despite conventional treatments (e.g., physiotherapy, medications, standard injections)

  • Wish to delay or avoid knee replacement surgery

  • Are looking for a durable non-surgical option to maintain mobility and quality of life

  • Individual suitability will be determined by clinical assessment.

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What to expect in clinic

1. Initial Consultation: At your first visit, the focus is on assessment and planning:

  • A detailed discussion about your symptoms and medical history

  • Clinical examination of the knee

  • Review of any existing imaging (X-rays or MRI scans)

  • Explanation of all suitable treatment options — both non-surgical and surgical

  • Agreement on whether Arthrosamid® is the right treatment for you

2. Arthrosamid® Injection Procedure: If Arthrosamid® is suitable, a separate appointment will be arranged for the injection:

  • Performed under ultrasound guidance for accurate placement

  • Local anaesthetic is given to ensure comfort

  • Six 1 ml vials of Arthrosamid® are injected into the knee joint

  • A small dressing is applied afterwards

  • You can go home the same day and resume normal daily activities

3. Aftercare & Recovery: Before you leave, you will be given clear advice on:

  • Activity modification and what to avoid in the first few days

  • Simple pain relief options if required

  • Rehabilitation guidance, including gentle exercises to support recovery

  • A follow-up appointment to review your progress and ensure the knee is settling well

Why Choose Arthrosamid®

Knee osteoarthritis is a progressive condition; while joint replacement remains a highly effective option, it may not suit all patients—particularly those seeking to prolong function, remain active, or avoid surgery for now. Arthrosamid® offers a validated alternative. 

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Within his private practice, Mr Khalid Malik offers Arthrosamid® injections as part of his advanced treatment options for knee osteoarthritis. His approach focuses on providing patients with access to the latest innovations in joint care, tailored decision-making, and personalised after-care — helping individuals move more comfortably and maintain a better quality of life.

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